Table 2.
Demographic and patient characteristics associated with DNa
| Predictor Variable | DNa Estimate (95% CI) (mEq/L) | |
|---|---|---|
| Facilities Where <90% of Patients Have the Same DNa (Individualized DNa) | Facilities Where 90%–100% of Patients Have the Same DNa (Nonindividualized) | |
| Male (versus female) | −0.08 (−0.15,0.00)a | 0.00 (−0.04,0.03) |
| Residual renal function (versus no RRF) | −0.17 (−0.26, −0.09)a | −0.02 (−0.07,0.02) |
| Diabetesb | −0.08 (−0.16,0.00) | −0.05 (−0.09, −0.01)a |
| Black race (versus non-black) | −0.15 (−0.32,0.03) | −0.09 (−0.18,0.01) |
| Comorbidities | ||
| hypertension | −0.24 (−0.33, −0.15)a | −0.02 (−0.06,0.03) |
| coronary artery disease | −0.10 (−0.18, −0.02)a | 0.02 (−0.02,0.06) |
| CVD other | 0.07 (−0.01,0.15) | −0.02 (−0.06,0.02) |
| congestive heart failure | 0.03 (−0.06,0.11) | 0.00 (−0.04,0.04) |
| peripheral vascular disease | 0.04 (−0.05,0.13) | −0.04 (−0.09,0.01) |
| cerebrovascular disease | 0.08 (−0.01,0.18) | 0.00 (−0.05,0.05) |
| psychiatric disorder | 0.09 (0.00,0.18) | 0.05 (−0.01,0.10) |
| cancer | 0.04 (−0.07,0.14) | 0.06 (0.01,0.12)a |
| lung disease | 0.05 (−0.05,0.16) | −0.01 (−0.07,0.06) |
| neurologic disease | 0.03 (−0.08,0.14) | −0.03 (−0.10,0.03) |
| recurrent cellulitis | −0.06 (−0.20,0.08) | 0.11 (0.03,0.19)a |
| gastrointestinal bleed | 0.05 (−0.10,0.20) | −0.03 (−0.11,0.05) |
| HIV | 0.87 (0.39,1.36)a | −0.15 (−0.42,0.12) |
| Vascular access | ||
| catheter (versus AVF) | 0.00 (−0.10,0.09) | −0.04 (−0.09,0.02) |
| graft (versus AVF) | 0.08 (−0.06,0.21) | −0.03 (−0.10,0.04) |
| unknown access (versus AVF) | −0.13 (−0.30,0.05) | 0.06 (−0.03,0.15) |
| Age (per 5 yr older) | 0.03 (0.02,0.04)a | −0.01 (−0.02,0.00)a |
| Vintage (per 1 yr longer) | 0.01 (0.01,0.02)a | 0.00 (0.00,0.01)a |
| Body mass index (per 5 units higher) | 0.05 (0.02,0.09)a | 0.02 (0.00,0.04)a |
| Facility characteristics | ||
| facility % Kt/V <1.2 (per 20% more) | −0.06 (−0.11, −0.02)a | −0.13 (−0.15, −0.10)a |
| facility % phosphorus <5.5 (per 20% more) | −0.24 (−0.30, −0.18)a | 0.01 (−0.02,0.04) |
| facility % catheter use (per 20% more) | −0.03 (−0.08,0.02) | −0.01 (−0.04,0.02) |
| Laboratory parameters | ||
| albumin (per 1 g/dl higher) | −0.02 (−0.09,0.06) | −0.13 (−0.17, −0.09)a |
| creatinine (per 1 mg/dl higher) | 0.00 (−0.02,0.01)a | 0.00 (−0.01,0.00) |
| ferritin (per 100 ng/ml higher) | 0.01 (0.00,0.01) | 0.00 (0.00,0.01) |
| hemoglobin (per 1 g/dl higher) | 0.03 (0.01,0.05) | 0.01 (0.00,0.02) |
| white blood cells (per 1000/mm3 higher) | 0.00 (−0.01,0.02) | −0.01 (−0.02,0.00)a |
| predialysis SNa (per 1 mEq/L higher) | 0.02 (0.01,0.03)a | 0.00 (0.00,0.01) |
CI, confidence interval; DNa, dialysate sodium concentration (prescribed); SNa, predialysis serum sodium concentration; RRF, residual renal function; CVD, cardiovascular disease; AVF, arteriovenous fistula.
a
Statistical significance.
b
Diabetes as comorbid condition or cause of ESRD.