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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Nat Chem Biol. 2011 Sep 25;7(11):818–826. doi: 10.1038/nchembio.670

Figure 4. PU-H71-identified proteins and networks are those important for the malignant phenotype.

Figure 4

(a) Representative western blot of sequential chemical precipitations, as indicated by the arrow, conducted in K562 extracts with the PU beads. (b) The effect of CARM1 knockdown on cell viability using tryptan blue (left) or acridine orange-ethidium bromide (right) staining was evaluated in K562 cells. Data are presented as means ± s.e.m. (n = 3). (c) The expression of select potential Hsp90-interacting proteins was analyzed by western blotting in K562 leukemia and Mia-PaCa-2 pancreatic cancer cells. (d) Representative western blot of single chemical precipitations conducted in Mia-PaCa-2 cell extracts with PU and control beads.