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. 2012 Jan 24;10(1):e1001249. doi: 10.1371/journal.pbio.1001249

Figure 3. The RIG-I signaling pathway is activated in IFNβ-producing cells.

Figure 3

(A and B) Western blots showing cytoplasmic (C) versus nuclear (N) distribution of different factors present in FACS-sorted cells 8 h.p.i. (A) and 12 h.p.i (B). (C) Western blots showing cytoplasmic distribution of signaling pathway proteins present in FACS-sorted cells 8 h.p.i. Arrows indicate MAVS protein. (D) qPCR analysis illustrating the expression levels of RIG-I, Trim25, and MDA5 genes in sorted IFNβ/YFP homozygous MEF cells 8 h.p.i. IB, immunoblot.