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. 2012 Jan 24;7(1):e30322. doi: 10.1371/journal.pone.0030322

Table 2. COX regression for pre-transplant influence factors of patient death.

Univariable analysis Multivariable analysis
Risk ratio (95% CI) P Risk ratio (95% CI) P
Early mortality (<30 d)
N-DGM (vs. ECT and DGM) 3.112 (1.331–7.273) 0.009 2.426 (1.002–5.881) 0.049
Delta-MELD 1.086 (1.006–1.173) 0.035
Hepatorenal syndrome 3.136 (1.404–7.005) 0.005 2.422 (1.047–5.600) 0.039
Infection 2.372 (1.065–5.281) 0.034
Serum sodium 0.927 (0.875–0.981) 0.008
Overall mortality
N-DGM (vs. ECT and DGM) 3.196 (1.623–6.294) 0.001 3.209 (1.499–6.869) 0.003
Delta-MELD 1.083 (1.018–1.152) 0.011
Hepatorenal syndrome 2.015 (1.050–3.867) 0.035
Serum sodium 0.938 (0.895–0.984) 0.009

Abbreviations: CI, confidence interval; DGM, downgraded MELD; ELT, emergency liver transplantation; MELD, model for end-stage liver disease; N-DGM, non-downgraded MELD.