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. 2012 Jan 24;7(1):e30283. doi: 10.1371/journal.pone.0030283

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Cerone, Neufeld.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The plots show that under a step-like stimulus an IFFL-1 generates a pulse-like response. When activates the FFL (A) the logic gate is activated by but is not inhibited by starting the expression of . Under the stimulation of , starts to build up, but it only inhibits the expression of after the delay required to reach the value (B). As a result starts decreasing when is still present. For the simulation the following parameters have been used: , , , , , , .

Inline graphic — The plots show that under a step-like stimulus an IFFL-1 generates a pulse-like response. When activates the FFL (A) the logic gate is activated by but is not inhibited by starting the expression of . Under the stimulation of , starts to build up, but it only inhibits the expression of after the delay required to reach the value (B). As a result starts decreasing when is still present. For the simulation the following parameters have been used: , , , , , , .