Figure 13. Oscillating transcription factor controlling the expression of gene 
by means of an IFFL-1 with AND gate.
The plot shows the response of a gene expressed under the stimulus of an oscillating transcription factor 
. The thresholds 
and 
split the signal 
into the two digital signals 
and 
(A). 
controls the expression of 
(B). The digital signals 
and 
are combined by the logic gate to finally control the expression of the gene 
(C). For the simulation the following parameters have been used: 
, 
, 
, 
, 
, 
, 
.