Figure 6. Novaluron modifies cuticle and epidermis aspect of Ae. aegypti larvae.

DIC microscopy was performed on histological sections of late L4 larvae stained with HE. (A) Control. Note the close association among cuticle, epidermis and the subjacent fat body layer. (B–D) Novaluron EI₉₉. Cuticle presents a semitransparent and discontinuous aspect being detached from the epidermis (B); epidermis is thinner (C) or degenerated, with a rope-like cuticle (D). ct: cuticle, did: disorganized imaginal disc, ep: epidermis, fb: fat body.