Table 2. Binding kinetics of the p75NTR-specific scFv as determined by surface plasmon resonance.
Ka (1/M⋅s) | kd (1/s) | Rmax (RU) | X2 | KD (M) | |
SH325-A11 | 2.44×105 | 1.57×10−3 | 156 | 2.31 | 6.5×10−9 |
SH325-B6 | 4.45×105 | 1.74×10−3 | 162 | 4.43 | 3.9×10−9 |
SH325-G7 | 1.08×105 | 4.22×10−3 | 180 | 0.24 | 3.9×10−8 |