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. 2012 Jan 24;7(1):e30747. doi: 10.1371/journal.pone.0030747

Figure 5. Chlamydial burden and levels of IL-8 do not differ between GPIC and CC13 infected guinea pigs during genital tract infection.

Figure 5

Groups of 5 untreated (A, B) or estradiol-treated (C, D) female guinea pigs were intravaginally infected with either GPIC or CC13 and sacrificed on day 30. (A) Monitoring of endocervical swabs during infection of untreated guinea pigs revealed that infectious bacteria were not detectable after day 9 for either strain. (B) Vaginal sponges collected through day 10 revealed similar levels of IL-8 in GPIC and CC13-infected guinea pigs. (C) The course of GPIC infection in estradiol-treated guinea pigs was prolonged compared to CC13. (D) IL-8 levels monitored during the first 10 days of infection were not different in estradiol-treated guinea pigs infected with GPIC and CC13. Bars represent the mean ± SD of five guinea pigs per group and each experiment was performed once.