Table 1. Incidence of lesions in tissues after intraperitoneal injection of chitosans and buffers.
| PBS | Glutamate buffer | ZWC (An/Am = 0.7) | Glycol chitosan | Chitosan glutamate | |
| Liver, capsule inflammation | 0/2a | 0/3 | 0/5 | 0/4 | 4/4 |
| Liver, capsular chitosan precipitates | 0/2 | 0/3 | 0/5 | 0/4 | 4/4 |
| Spleen, capsule inflammation | 0/2 | 0/3 | 0/5 | 0/4 | 3/4 |
| Spleen, capsular chitosan precipitates | 0/2 | 0/3 | 0/5 | 0/4 | 3/4 |
| Body wall, inflammation | 0/2 | 0/3 | 0/5 | 1/4 | 3/4 |
| Body wall, chitosan precipitates | 0/2 | 0/3 | 0/5 | 0/4 | 0/4 |
| Peritoneal fluid, inflammation | 0/2 | 0/4 | 0/5 | 3/3 | 4/4 |
| Peritoneal fluid, chitosan precipitates | 0/2 | 0/4 | 0/5 | 3/3 | 4/4 |
a
Incidence of occurrence: Number of mice with lesion/total number of mice examined.