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. Author manuscript; available in PMC: 2012 Jan 25.
Published in final edited form as: Nat Struct Mol Biol. 2011 May 1;18(5):550–555. doi: 10.1038/nsmb.2039

Table 1.

Binding constants of the C3G-ligand to the nSH3 domain of various states of Crk

Proteins KD (nM) 1Stability (referenced to Crk-I)
(kcal mol−1)
2Crk-I 22.5 ± 1.3 -
Crk-II 285.5 ± 19.0 1.5 ± 0.1
1

Stabilities were calculated from KO (Methods)

2

ref. 8