Fig. 4.

Stretch injury activates RLR signaling in primary astrocytes in culture. Representative immunoblot analysis of astrocyte lysates of non-stretch (C, control) and stretch cells harvested at 15 min, 30 min and 1h after stretch injury. Cell lysates were immunoblotted with antibodies against Rig-I, MDA5, VISA and phosphorylated IRF3. β-actin was used as internal standard and control for protein loading. Data presented as mean +/− SEM. *p < 0.05. n=6.