Table 5.
Cartilage T2 values (ms) of subjects with and without OA risk factors for the deep and superficial cartilage layer as well as the whole compartment. Values printed in bold indicate statistically significant differences between subject groups (p<0.05).
| Subjects with OA risk factors (n=101) |
Subjects without OA risk factors (n=41) |
p-value* | |
|---|---|---|---|
| baseline T2 patella (deep layer) | 29.9±3.7+ | 29.4±3.3~ | 0.304 |
| 24 month T2 patella (deep layer) | 31.0±3.2+ | 30.9±3.2~ | 0.836 |
| baseline T2 patella (superficial layer) | 33.6±2.9+ | 33.9±3.8~ | 0.613 |
| 24 month T2 patella (superficial layer) | 35.4±3.7+ | 35.7±3.0~ | 0.557 |
| baseline T2 patella (whole compartment) | 31.7±2.8+ | 31.7±3.3~ | 0.744 |
| 24 month T2 patella (whole compartment) | 33.2±3.1+ | 33.3±2.5~ | 0.811 |
| delta T2 patella (whole compartment) | 1.3±2.7 | 1.7±2.6 | 0.449 |
| baseline T2 medial femur (deep layer) | 35.7±2.3 + | 34.6±2.3 # | 0.016 |
| 24 month T2 medial femur (deep layer) | 36.3±2.9 + | 35.0±2.1 # | 0.027 |
| baseline T2 medial femur (superficial layer) | 40.0±2.7- | 39.2±2.6# | 0.196 |
| 24 month T2 medial femur (superficial layer) | 40.1±2.9 | 38.6±2.4 # | 0.016 |
| baseline T2 medial femur (whole compartment) | 37.9±2.3 - | 36.9±2.3 # | 0.044 |
| 24 month T2 medial femur (whole compartment) | 38.2±2.7 - | 36.8±2.1 # | 0.013 |
| delta T2 medial femur (whole compartment) | 0.4±2.5 | −0.1±1.4 | 0.731 |
| baseline T2 averaged over all five compartments (deep layer) |
30.7±2.1+ | 30.1±1.6~ | 0.059 |
| 24 month T2 averaged over all five compartments (deep layer) |
31.6±2.9+ | 30.9±1.4~ | 0.276 |
| baseline T2 averaged over all five compartments (superficial layer) |
34.5±2.0+ | 34.1±1.7~ | 0.267 |
| 24 month T2 averaged over all five compartments (superficial layer) |
37.0±2.5+ | 36.1±1.5~ | 0.138 |
| baseline T2 averaged over all five compartments (whole compartment) |
32.7±1.8+ | 32.1±1.5~ | 0.099 |
| 24 month T2 averaged over all five compartments (whole compartment) |
34.3±2.6+ | 33.5±1.4~ | 0.175 |
| delta T2 averaged over all five compartments (whole compartment) |
1.7±2.5 | 1.4±1.0 | 0.983 |
*
Adjusted for age, gender, BMI and baseline KL-score.
+
p<0.05 for paired t-test for change in T2 over 24 months in subjects with OA risk factors
-
p>0.05 for paired t-test for change in T2 over 24 months in subjects with OA risk factors
~
p<0.05 for paired t-test for change in T2 over 24 months in subjects without OA risk factors
#
p>0.05 for paired t-test for change in T2 over 24 months in subjects without OA risk factors