TABLE 1.
10-5 M | 10-4 M | 2×10-4 M | 5×10-4 M | |
---|---|---|---|---|
Total contractile activity (AUC)† | -9±3 | -14±2** | -28±7** | -44±3** |
Amplitude | -2±1 | -4±1 | -7±2 | -12±1 |
Baseline tone | -4±1 | -4±1 | -4±1 | -5±1 |
Frequency | -5±2 | -10±2 | -26±2** | -58±3** |
Percent change from baseline contractile activity, baseline defined as zero; mean±SEM; n=15 rats
Area under the contractile curve
p<0.05 compared to baseline contractile activity defined as 0%