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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Oct 10;1823(2):406–419. doi: 10.1016/j.bbamcr.2011.09.012

Figure 5. Regulatory elements of the human TGM2 gene expression.

Figure 5

The expression of TG2 is regulated by many factors. In this figure identified elements that regulate TG2 expression are shown. Retinoic acid response elements: RRE-1 (-1731), RRE-2 (-1720), glucocorticoid response element: GRE (-1399), nuclear factor κB response element: NF-κB (-1338), interleukin-6 response element:IL-6 (-1190), tumor growth factor-β1: TGF-β1 (-900), activator protein-2: AP-2 (-634), hypoxia response element: HRE (-367), activator protein-1: AP-1 (-183), CAAT box (-96), GC box: Sp1 binding motifs (-54, -43, +59, +65), TATA box (-29), nuclear factor-1: NF-1 (+4, +12).