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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Ann Thorac Surg. 2011 Dec 28;93(2):457–463. doi: 10.1016/j.athoracsur.2011.09.057

Table 4.

MMP protein abundance to TIMP score (TS = TIMP-1+TIMP-3+TIMP-4) ratios for normal and aneurysmal aorta from all BAV patients or BAV patients with different valve morphologies (L-N, R-L, R-N). Values (mean ± SEM) are expressed as a percent of normal aorta

MMP/TS Ratio Normal BAV L-N R-L R-N
MMP-1/TS 100±17 136±21 75±30 164±28 * 82±19
MMP-2/TS 100±13 180±16 * 220±29 * 167±20 * 203±39 *
MMP-3/TS 100±18 138±19 197±32 * 130±26 123±34
MMP-7/TS 100±10 74±8 * 124±41 67±6 *# 65±17
MMP-8/TS 100±43 50±9 * 21±8 * 61±12 * 31±8 *
MMP-9/TS 100±41 360±76 * 196±44 432±104 * 178±66
MMP-12/TS 100±31 178±24 * 213±60 168±28 * 182±66
*

p<0.05 versus reference normal value of 100;

#

p<0.05 versus L-N group