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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Ann Thorac Surg. 2011 Dec 28;93(2):457–463. doi: 10.1016/j.athoracsur.2011.09.057

Table 5.

MMP protein abundance to TIMP score (TS = TIMP-1+TIMP-2+TIMP-3+TIMP-4) ratios for normal and aneurysmal aorta from all BAV patients or BAV patients with different valve morphologies (L-N, R-L, R-N). Values (mean ± SEM) are expressed as a percent of normal aorta

MMP/TS Ratio Normal BAV L-N R-L R-N
MMP-1/TS 100±20 123±21 49±11 * 153±29 71±15
MMP-2/TS 100±9 172±12 * 232±46 * 155±12 * 183±28 *
MMP-3/TS 100±13 134±14 * 237±47 * 109±11 # 139±34
MMP-7/TS 100±12 66±8 * 139±51 59±4 *# 41±9 *#
MMP-8/TS 100±46 54±8 * 45±19 * 61±10 * 34±9 *
MMP-9/TS 100±41 343±61 * 211±68 403±83 * 199±60
MMP-12/TS 100±28 169±24 * 218±92 172±28 * 126±48
*

p<0.05 versus reference normal value of 100;

#

p<0.05 versus L-N group