Table 6.

Mean asymmetry (s) values for various concentration-effect curve groupings^a

Concentration-effect curves	n	mean s ± s.d.	min. s	max. s
all single-chemical and mixture curves	648	1.01 ± 1.12	0.10	10.00
Single agent curves
full TDT agent	159	0.50 ± 0.16	0.16	0.93
no or partial TDT agent	273	1.35 ± 1.43	0.10	10.00
Mixture curves
full TDT for both agents	45	0.47 ± 0.12	0.26	0.73
full TDT agent w/a no or partial TDT agent	66	0.80 ± 0.72	0.17	3.67
partial TDT agent w/a no or partial TDT agent	105	1.25 ± 1.15	0.17	10.00

^afull TDT – agent typically has time-dependent toxicity (TDT) > 100%

partial TDT – agent typically has TDT between about 10 and 90%

no TDT – agent typically has TDT <10% (see Dawson et al., 2008; 2010; 2011)