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KSR1 attenuates ERK activation in GDC0879, but not PLX4720-treated cells. A549 cells expressing either the pLKO.1 vector or pLKO.1-KSR1 shRNA were treated as indicated for 1 hr. Lysates were analyzed for pERK and tubulin levels. Depletion of KSR1 is also shown.
