Extracellular signaling factors |
TGFβ superfamily: TGFα, TGFβ, EGFR, Msx1, BMP, Activns, Hand2 |
71 |
30.1% |
|
Platelet derived growth factor: PDGF-C |
8 |
3.4% |
|
Fibroblast growth factor: FGF |
21 |
8.9% |
|
Sonic Hedgehog: Shh, PTCH, SMO, CBP |
13 |
5.5% |
|
WNT: Wnt, Dv, Fz |
13 |
5.5% |
|
Total: |
126 |
53.4% |
Transcription Factors |
FFAP2a, AP-2a, IR F6, FOXE1, TTF-2, GLI, SMAD1, Mnt, Phf8 |
31 |
13.1% |
T-box Transcription Factors/Protein Modification |
TBX22, TBX1, TBX10, Mn1, SUMO, p63, SATB2 |
17 |
7.2% |
Cell adhesion molecules |
PVRL1, Nectin, Integrin, E-cadherin, Desmosomal protein, Crk |
10 |
4.2% |
Extracellular Matrix |
Collagen, GAG, CSPG, HA, MMP |
8 |
3.4% |
Other Factors |
Jag, Notch, GABA, RA, Snai1, Snai2, Runx2, Meox, Pax1, Pax3, PDS5B, FAF, Sox9, MYH9, Zfhep, DIg |
27 |
11.4% |
Cholesterol Pathway |
Sterol, Insig 1, Insig 2 |
2 |
0.85% |
Kinase Cascades |
NAT2, MAPK, CRE B, PKA, camp, Eph, RTK, p57Kip2
|
10 |
4.2% |
Genes |
JARID2, ADAMTS9/20, TFAP2A, RBM10, Hoxc5 |
5 |
2.1% |