Representative images of β-gal-positive and β-gal-negative stripes in adult 21OH/LacZ transgenic adrenal cortex sections. (A and B) hemizygous female, (C and D) homozygous female, (E and F) hemizygous male and (G and H) homozygous male 21OH/LacZ transgenic mice at 8 (A, C, E and G) and 52 (B, D, F and H) weeks of age. Adrenal glands were frozen-sectioned and stained for β-gal. Dark stripes in the photographs were stained blue (β-gal-positive). Scale bar, 0.2 mm.