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. 2011 Mar 15;17(2):223–233. doi: 10.1038/mp.2011.24

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Copyright © 2012 Macmillan Publishers Limited

This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Association of SNP genotypes with Aβ₁₋₄₂ cerebrospinal fluid (CSF) levels. CSF Aβ₁₋₄₂ levels (pg ml⁻¹) measured in patients carrying different single-nucleotide polymorphism (SNP) genotypes. Because of high r² values between rs646817 and rs1746659, and between rs12034383 and rs11803956, only results for rs646817 and rs12034383 are shown. Significant pairwise comparisons are indicated, that is, AA vs AG+GG for rs646817 and AA vs GG for rs12034383, with P-values corrected for age at lumbar puncture, disease duration at lumbar puncture, gender and APOE ɛ4 genotype. For rs646817, results of the association test under a dominant model are depicted.