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. 2011 Jul 1;1(4):128–132. doi: 10.4161/cl.1.4.18738

Table 1.

Ank T4SS effectors with known functions

Ank Number of repeats Other domains/motifs Interacting host protein Function Pathogen host cell References
Anaplasma
AnkA 11 EPIYA motif SHP-1, Abi-1 Binds eukaryotic DNA, influences CYBB expression Neutrophil 1316
Legionella
AnkB 2 F-box domain Parvin B Recruitment of ubiquitinated proteins to the Legionella-containing vacuole 26, 2830, 33, 34
AnkH
AnkJ
2
3
Unknown Required for intracellular replication Macrophage 22
AnkX 4 FIC domain Rab1 and Rab35 Phosphocholine transferase that regulates Rab1 and Rab35 activity 25
Coxiella
AnkG 2 p32 (gC1qR) Inhibits apoptosis Macrophage 41