Table 2.
Variable | CABG Alone (N = 499) | CABG with Surgical Ventricular Reconstruction (N = 501) | Hazard Ratio (95% CI) | P Value |
---|---|---|---|---|
number (percent) | ||||
Outcome
| ||||
Death from any cause or hospitalization for cardiac causes | 292 (59) | 289 (58) | 0.99 (0.84–1.17) | 0.90 |
| ||||
Death from any cause | 141 (28) | 138 (28) | 1.00 (0.79–1.26) | 0.98 |
| ||||
Death from any cause within 30 days after randomization (intention-to-treat analysis) | 22 (4) | 30 (6) | 0.26 | |
| ||||
Death from any cause within 30 days after surgery†
| ||||
Intention-to-treat analysis | 25 (5) | 26 (5) | 0.88 | |
| ||||
As-treated analysis | 23 (5) | 28 (6) | 0.40 | |
| ||||
Hospitalization
| ||||
For any cause | 272 (55) | 268 (53) | 0.98 (0.83–1.16) | 0.82 |
| ||||
For cardiac causes | 211 (42) | 204 (41) | 0.97 (0.80–1.18) | 0.73 |
| ||||
Acute myocardial infarction | 22 (4) | 20 (4) | 1.01 (0.54–1.87) | 0.96 |
| ||||
Stroke | 31 (6) | 23 (5) | 0.77 (0.45–1.32) | 0.35 |
| ||||
Subsequent procedure‡
| ||||
CABG | 0 | 1 (<1) | ||
| ||||
Placement of left ventricular assist device | 2 (<1) | 2 (<1) | ||
| ||||
Heart transplantation | 2 (<1) | 7 (1) | ||
| ||||
Percutaneous coronary intervention | 32 (6) | 17 (3) | ||
| ||||
Placement of pacemaker
| ||||
For resynchronization | 31 (6) | 30 (6) | ||
| ||||
For heart rate | 44 (9) | 47 (9) | ||
| ||||
Placement of implantable cardioverter–defibrillator | 100 (20) | 86 (17) |
Hazard ratios are for coronary-artery bypass grafting (CABG) with surgical ventricular reconstruction as compared with CABG alone.
For the analysis of death within 30 days after surgery, in the group that was assigned to undergo CABG alone, 490 patients were evaluated in the intention-to-treat analysis and 498 patients in the as-treated analysis; in the group that was assigned to undergo CABG with surgical ventricular reconstruction, 489 patients were evaluated in the intention-to-treat analysis and 481 patients in the as-treated analysis.
Hazard ratios and P values are not provided for subsequent procedures because of the low incidence of these events.