Figure 8.

IL-1β concentrations increase in the ipsilateral cortex following a controlled cortical impact. Within four hours of a brain injury, IL-1β increases (p < 0.05) in the ipsilateral cortex in comparison to both control and contralateral tissue. The expression of IL-1β remained elevated for the first 24 hours after injury, and did not return to levels observed in control or contralateral tissue (p > 0.05) until three days post-injury. At no time, was the expression of IL-1β observed to be elevated (p > 0.05) in the contralateral cortex in comparison to control. All values are mean ± SEM, n = 5. ^*At each time point noted, ipsilateral differs from control tissue, p < 0.05. Differences between the ipsilateral and contralateral cortices are denoted by placing the appropriate p-value above the two bars.