TABLE 2.
INCIDENCE RATE RATIO FOR THE ASSOCIATION OF HIV INFECTION AND PULMONARY DISEASES STRATIFIED BY AGE IN MULTIVARIATE POISSON REGRESSION MODELS WITH AND WITHOUT ADJUSTING FOR SMOKING
| Incidence Rate Ratio (95% confidence interval) for HIV Infection |
||||
|---|---|---|---|---|
| Virtual Cohort |
Nested Sample of Virtual Cohort Merged with LHS, Adjusting For Having Ever Smoked |
|||
| Condition | Age <50 yr | Age ≥50 yr | Age <50 yr | Age ≥50 yr |
| COPD | 1.17 (1.11–1.24)* | 1.08 (1.01–1.15)* | 1.25 (1.08–1.43)* | 1.11 (0.96–1.29) |
| Asthma | 0.97 (0.89–1.06) | 0.93 (0.80–1.08) | 0.90 (0.64–1.27) | 0.87 (0.62–1.24) |
| Lung cancer | 2.13 (1.78–2.57)* | 1.73 (1.47–2.04)* | 2.28 (1.29–4.02)* | 1.76 (1.23–2.50)* |
| Pulmonary hypertension | 1.53 (1.21–1.93)* | 1.57 (1.23–2.00)* | 1.00 (0.48–2.10) | 1.66 (1.03–2.68)* |
| Pulmonary fibrosis | 1.59 (1.22–2.08)* | 1.45 (1.10–1.94)* | 1.78 (0.91–3.48) | 1.79 (1.01–3.14)* |
| Bacterial pneumonia | 5.09 (4.77–5.42)* | 2.84 (2.61–3.10)* | 4.24 (3.55–5.05)* | 2.44 (2.02–2.96)* |
| TB | 5.97 (4.98–7.16)* | 5.43 (4.03–7.30)* | 4.96 (2.96–8.29)* | 8.89 (4.07–19.4)* |
Definition of abbreviations: COPD = chronic obstructive pulmonary disease; LHS = 1999 Veterans Large Health Survey; TB = tuberculosis.
All models are adjusted for age as a continuous variable, race and ethnicity, sex, alcohol disorders, drug abuse, and hepatitis C infection. Models using the nested sample of the Virtual Cohort merged with the LHS are additionally adjusted for having ever smoked. Full models with incidence rate ratios for all predictors are shown in Tables E2 and E3. The incidence rate ratio for Pneumocystis pneumonia is >100 in all models.
*
P < 0.05.