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Diagnostic CIMP-defining gene marker panel based on the Infinium DNA methylation data. A dichotomous heatmap of the Infinium DNA methylation data is shown. (Black bars) DNA methylation β-value ≥0.1; (white bars) DNA methylation β-value <0.1. The panel of five markers shown on the top (CIMP-H & CIMP-L) is used to identify CIMP-H and CIMP-L tumors. The panel of five markers shown on the bottom (CIMP-H specific) is used to specifically identify CIMP-H tumors.
