Figure 2.

Bisulfite sequencing of the B3GAT2 promoter. The B3GAT2 promoter is an example of a hypermethylation site shared by all tumors but is more extensively methylated in CIMP tumors. The UCSC Genome Browser screen capture shows the DNA methylation signal in each sample. The rectangles mark the regions validated by bisulfite sequencing and are color-coded to the corresponding bisulfite sequencing data. Each circle represents a CpG dinucleotide. (Black circles) Methylated cytosines; (white circles) unmethylated cytosines.