Table 1.
Plasmodium vivax Recurrences in Mothers and Infants
| Mothers (n = 12) | Infants (n = 21) | P Value | |
| No. of recurrent Plasmodium vivax infections | 8 | 9 | >.2 |
| No. of recurrences documented, median (range) | 2.5 (1–5) | 2.5 (1–6) | >.2 |
| Interval of recurrence, days, median (range) | 45 (21–82) | 37 (11–168) | |
| First recurrence similar to initial infection | 2/8 A | 7/9 A | .02 |
| 1 indeterminate | 1 indeterminate | ||
| Second recurrence similar to initial infection | 1/6 A | 3/6 A | >.1 |
| 1 indeterminate | 1/6 B | ||
| Third recurrence similar to initial infection | 1/4 B | 2/5 A | .5 |
| 1 indeterminate | 1 indeterminate | ||
| Fourth recurrence similar to initial infection | 0/1 | 2/2 A | .3 |
| Fifth recurrence similar to initial infection | 0/1 | 1/1 B | .5 |
| Sixth recurrence similar to initial infection | … | 1/1 A | … |
| Proportion of recurrences that were genotypically similar | 4/20 | 17/24 | .02 |
| 3 indeterminate | 2 indeterminate | ||
| In genotypically different recurrences, median proportion of different alleles (range) | 80% (50%–100%) | 63% (57%–86%) | .008 |
Criteria for interpretation: A = 0, 1 marker (loci) different or 2 markers (loci) different with ≤1 possible stepwise mutation; B = 3 markers (loci) different but ≤1 repeat unit, different with ≤1 possible stepwise mutation; indeterminate: ≥5 markers (loci) failed to amplify.