Table 1.
Association of different patient and tumor specific characteristics with CAV1 protein expression in the tumor cytoplasm.
| Variable | CAV1 in tumor cytoplasm ≤ median | CAV1 in tumor cytoplasm > median | p-value | Test |
|---|---|---|---|---|
| Age (mean; ± SD) | 60.4 ± 11.5 years | 59.3 ± 11.1 years | 0.40 | t-test |
| Sex | 0.04 | Fisher's exact | ||
| female | 79 (50.6%) | 51 (38.3%) | ||
| male | 77 (49.4%) | 82 (61.7%) | ||
| Stage (TNM 2002) | 0.54 | Chi2 | ||
| pT1 | 5 (3.2%) | 3 (2.3%) | ||
| pT2 | 86 (55.1%) | 64 (48.1%) | ||
| pT3 | 58 (37.2%) | 57 (42.9%) | ||
| pT4 | 7 (4.5%) | 9 (6.7%) | ||
| LN metastasis1 | 0.04 | Fisher's exact | ||
| pN0 | 78 (89.7%) | 70 (77.8%) | ||
| pN+ | 9 (10.3%) | 20 (22.2%) | ||
| Pulmonal/visceral metastasis1 | 0.23 | Fisher's exact | ||
| M0 | 124 (82.7%) | 93 (76.2%) | ||
| M+ | 26 (17.3%) | 29 (23.8%) | ||
| Grade | 0.04 | Chi2 | ||
| G1 | 30 (21.6%) | 20 (17.7%) | ||
| G2 | 103 (74.1%) | 78 (69.0%) | ||
| G3/4 | 6 (4.3%) | 15 (13.3%) |
1 at time of renal surgery.
Abbreviations: CAV1 = caveolin 1, RCC = renal cell carcinoma, SD = standard deviation, LN = lymph node.