Table 2.
Association of different patient and tumor specific characteristics with CAV1 protein expression in tumor membranes.
| Variable | CAV1 in tumor membranes ≤ median | CAV1 in tumor membranes > median | p-value | Test |
|---|---|---|---|---|
| Age (mean; ± SD) | 59.9 ± 11.7 years | 59.8 ± 10.8 years | 0.99 | t-test |
| Sex | 0.03 | Fisher's exact | ||
| female | 87 (50.3%) | 43 (37.1%) | ||
| male | 86 (49.7%) | 73 (62.9%) | ||
| Stage (TNM 2002) | 0.54 | Chi2 | ||
| pT1 | 4 (2.3%) | 4 (3.4%) | ||
| pT2 | 91 (52.6%) | 59 (50.9%) | ||
| pT3 | 66 (38.2%) | 49 (42.2%) | ||
| pT4 | 12 (6.9%) | 4 (3.4%) | ||
| LN metastasis1 | 1.00 | Fisher's exact | ||
| pN0 | 86 (83.5%) | 62 (83.8%) | ||
| pN+ | 17 (16.5%) | 12 (16.2%) | ||
| Pulmonal/visceral metastasis1 | 0.54 | Fisher's exact | ||
| M0 | 133 (81.1%) | 84 (77.8%) | ||
| M+ | 31 (18.9%) | 24 (22.2%) | ||
| Grade | 0.28 | Chi2 | ||
| G1 | 30 (20.2%) | 20 (19.4%) | ||
| G2 | 110 (73.8%) | 71 (68.9%) | ||
| G3/4 | 9 (6.0%) | 12 (11.7%) |
1 at time of renal surgery.
Abbreviations: CAV1 = caveolin 1, RCC = renal cell carcinoma, SD = standard deviation, LN = lymph node.