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Circulating IGF-I and IGFBP-3 levels change according to disease status in BL patients. a. The box-plot represents the serum levels of IGF-I assessed in nonreactional (NR BL) and reactional BL (R BLt = 0) patients at the pre-MDT stage. Median values are indicated by lines (-). b. Represent the serum levels of IGF-I at the pre-MDT stage and during RR (R BLRR). Each line represents one patient. Paired t test was used for statistical analysis.
