Table 1. Loss of heterozygosity (LOH) and mutation in sporadic vestibular schwannomas.

No	Exon	DNA sequence alteration	Codon change	Consequence	LOH
					D22S268	D22S275	D22S929
1	2	c.136T>G (p.L46R)	46	Missense	+	+	+
2	3	c.363+1G>A	-	Splicing donor site	+	+	+
3	-	-	-	-	+	+	+
4	2, 3	c.232_233 ins G c.303T>A (p.Y101X)	78 101	Frameshift, Nonsense
6	3	c.280 del T	94	Frameshift	+	+	+
8	2	c.122G>A (p.W41X)	41	Nonsense
10	13	c.1379 del T	460	Frameshift
12	2	c.169C>T (p.R57X)	57	Nonsense	+	+	+
13	12	c.133 C>G (p.S444X)	444	Nonsense	+	+	+
14	-	-	-	-	+	+	+
15	2	c.154_175del22	51–59	Frameshift
17	10	c.955C>T (p.Q319X)	319	Nonsense
21	10	c.963_964 ins A	322	Frameshift		+
22	14	c.1568_1574+7del14	523–525+intron7bp	Frameshift
24	7, 8	c.616G>T (p.E206X) c.694_771del78	206 232–257	Nonsense In-frame deletion
27	4	c.364-8_408del53	Intron8bp+122–136	Frameshift
29	2	c.169C>T (p.R57X)	57	Nonsense
30	4	c.394 delT	132	Frameshift	+	+	+