Table 3. Did Unilateral and Bilateral DBS Lead Placement Impact the Pre-operative Diagnosis of DDS?
| Patient | Pre-operative Diagnosis | Diagnosis after Unilateral DBS Placement* (Target) | Diagnosis after Bilateral DBS Placement* (Targets) |
| 1 | DDS | DDS (STN) | ** |
| Need for excessive DRT, frequent rescue doses, development of withdrawal state with dose reduction | Need for excessive DRT, frequent rescue doses, development of withdrawal state with dose reduction | ||
| 2 | DDS | DDS (GPi) | DDS (GPi, GPi) |
| Need for excessive DRT, self-medicating, development of withdrawal state with dose reduction | Need for excessive DRT, development of withdrawal state with dose reduction | Need for excessive DRT, development of withdrawal state with dose reduction | |
| 3 | DDS | DDS (STN) | DDS (STN, STN) |
| Need for excessive DRT, self-medicating, development of withdrawal state with dose reduction | Need for excessive DRT, self-medicating, development of withdrawal state with dose reduction, unwilling to reduce dosage | Need for excessive DRT, self-medicating, development of withdrawal state with dose reduction, unwilling to reduce dosage | |
| 4 | DDS | DDS (STN) | DDS (STN, STN) |
| Need for excessive DRT, unwilling to reduce dosage, development of withdrawal state with dose reduction | Need for excessive DRT, unwilling to reduce dosage, development of withdrawal state with dose reduction, increased need for DRT despite excessive dyskinesias | Need for excessive DRT despite being able to decrease dosage, increased need for DRT despite excessive dyskinesias | |
| 5 | ICD and DDS | ICD and DDS (GPi) | ICD and DDS (GPi, GPi) |
| Pathological gambling and shopping | Need for excessive DRT, excessive spending and gambling, excessive money spent on adult entertainment, cannot maintain finances | Need for excessive DRT, excessive spending and gambling, excessive money spent on adult entertainment, cannot maintain finances |
*DBS unilateral or bilateral lead target(s) noted in parentheses.
**Patient did not have bilateral DBS lead placement.
DRT; dopamine replacement therapy including levodopa and/or dopamine agonists.