Table 5. Clinical outcome and cell -mediated and humoral-immune reconstitution after BMT in 10 RAG2-deficient SCID patients.

Patient	months post BMT	IVIG	ALC	CD3	CD4	CD8	CD56	CD20	PHA -SI	IGG	IGA	IGM	Chimerism in lymph (%)	Outcome
P1	24	yes	632	430	152	316	90	6	2.6%	486	19	27	30	Died
P2	24	yes	1840	1564	846	644	60	18	62%	ND	ND	ND	34	Died
P3	76	yes	873	306	279	105	20	61	35%	480	UD	UD	100	Alive, cGVHD
P4	72	No	2134	1643	597	1003	105	192	39%	642	118	96	50	Alive, cGVHD
P5	120	yes	2346	1947	1173	868	115	47	50%	2180	63	401	100	Alive, cGVHD
P6	6	No	1212	720	480	300	40	120	260%	ND	ND	ND	80	Alive and Well
P7	34	No	4506	3154	1262	1622	450	541	89%	ND	ND	ND	100	Alive and Well
P8	30	No	5084	3711	2695	1118	200	763	86%	1120	75	78	100	Alive and Well
P9	3	yes	747	234	112	127	350	3	ND	1110	UD	20	100	Alive and Well
P10	8	yes	2702	1973	598	1189	270	162	ND	438	UD	18	100	Alive and Well

ND-not done, UD-undetectable, PHA – phytohemagglutinin, SI – stimulation index (patient/control), ALC - absolute lymphocyte count.