Table 5. Correlation analyses between angiogenic markers and miR-155 expression in NSCLC patients.
miR-155 | |||
Total cohort (n = 335) | N0 (n = 232) | N+ (n = 103) | |
VEGF-A | r = 0.09, P = 0.11 | r = 0.05, P = 0.50 | r = 0.18, P = 0.07 |
PDGF-B | r = 0.04, P = 0.49 | r = 0.06, P = 0.37 | r = 0.01, P = 0.96 |
HIF-1α | r = 0.02, P = 0.68 | r = 0.02, P = 0.75 | r = −0.1, P = 0.27 |
FGF2 | r = 0.17, P = 0.002 | r = 0.06, P = 0.35 | r = 0.34, P<0.001 |
Abbreviations: VEGF-A, vascular endothelial growth factor-A; PDGF-B, platelet derived factor -B; HIF-1α, hypoxia inducible factor 1α; FGF2, fibroblast growth factor 2; N0, lymph node negative patients; N+, lymph node positive patients.