Table 3. Association between SNPs located in CNV207 and CNV1836 region and alcohol drinking.
CNV region | CHR | SNP | Discovery sample | Replication sample | ||||
Allelea | MAF | P-valueb | Allelea | MAF | P-valueb | |||
CNV207 | 2 | rs7593687 | A/G | <0.01 | NA | A/G | <0.01 | NA |
2 | rs7583665 | T/C | 0.02 | 0.75 | T/C | <0.01 | NA | |
CNV1836 | 12 | rs10772040 | A/C | 0.09 | 0.88 | C/A | 0.22 | 0.08 |
12 | rs983985 | C/T | 0.37 | 0.19 | T/C | 0.04 | 0.16 | |
12 | rs7972327 | C/G | 0.09 | 0.99 | G/C | 0.12 | 0.97 | |
12 | rs2018498 | A/G | 0.37 | 0.19 | G/A | 0.04 | 0.16 |
. The second allele is the minor allele in the sample;
. NA: not available due to the low minor allele frequency.