. Author manuscript; available in PMC: 2013 Feb 1.

Published in final edited form as: Psychopharmacology (Berl). 2011 Aug 24;219(4):1089–1097. doi: 10.1007/s00213-011-2438-6

Table 1.

Cocaine self-administration parameters in rats classified as LCRs or HCRs at the end of the 14-session experiment.

Cocaine Dose (mg/kg/inf)		Cocaine-induced locomotor activity (cm/30 min)		Avg. Cocaine Intake (14 days; mg/kg)	Avg. Cocaine Intake (X to X+3; mg/kg)	Overall Percent Acquisition
Cocaine Dose (mg/kg/inf)		All Rats	Acquisition Rats	Avg. Cocaine Intake (14 days; mg/kg)	Avg. Cocaine Intake (X to X+3; mg/kg)	Overall Percent Acquisition
0.1875	LCR (n=13)	1396 ± 220	-	-	-	8% (1/13)
0.1875	HCR (n=12)	5761 ± 915	-	-	-	8% (1/12)
0.375	LCR (n=13)	883 ± 188	932 ± 513^*	12.7 ± 4.4	8.8 ± 1.5	31% (4/13)
0.375	HCR (n=14)	5331 ± 536	5019 ± 645^*	10.1 ± 2.2	11.0 ± 1.5	64% (9/14)
0.5	LCR (n=9)	1560 ± 233	1391 ± 371^*	10.9 ± 5.0	14.8 ± 2.9	67% (6/9)^**
0.5	HCR (n=9)	5496 ± 711	4207 ± 791^*	13.7 ± 3.6	14.1 ± 2.3	56% (5/9)
1.0	LCR (n=11)	1901 ± 309	1480 ± 292^*	16.2 ± 2.5	12.3 ± 2.1	82% (9/11)
1.0	HCR (n=11)	5523 ± 440	5468 ± 434^*	13.7 ± 3.0	14.1 ± 2.5	91% (10/11)
1.5	LCR (n=14)	1511 ± 265	1361 ± 306^*	12.0 ± 4.4	19.3 ± 3.2	57% (8/14)
1.5	HCR (n=13)	6026 ± 744	5771 ± 576^*	17.7 ± 3.4	16.8 ± 2.4	77% (10/13)

Cocaine-induced locomotor activity in rats that acquired cocaine self-administration and were used in intake analyses.

^**

See Exclusions and exceptions section of methods for description of different n values between overall intake and percent acquisition analysis for this dose.