FIG. 4.
Alignment of sorbitol dehydrogenase proteins. Shown are the P. infestans protein (from pisp3) and proteins from N. crassa (GenBank accession no. NCU00891), C. albicans (AAC24597), S. cerevisiae (NP0100035), Drosophila melanogaster (AAD00902), and the bacterium Morganella morganii (AAA25324.1). Indicated at the top of the alignment are regions in contact with metal ions (M) or the NAD ligand (L). The solid squares represent blocks of identity, and the shaded squares represent blocks of similar amino acids.