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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Eur J Pain. 2012 Feb;16(2):170–181. doi: 10.1016/j.ejpain.2011.07.002

Fig. 5.

Fig. 5

Effects of μ and κ opioid receptors on EA action. Data are presented as mean ± SE (n=8 per group). 5A: Antagonists, CTOP for μ and nor-BNI for κ, were infused into the rACC in saline-injected, sham EA-treated rats. The rats showed no CPA. 5b. Antagonists were infused in CFA-injected, sham EA-treated rats. The rats showed significant CPA. *P<0.05 vs pre-conditioning test results. 5C. Antagonists were infused in saline-injected, EA-treated rats. The rats showed no CPA. 5D: Opioid receptor antagonist effects on EA inhibition of a CFA-induced affective response. EA was given on day two before pain-paired conditioning. CTOP or nor-BNI was given prior to EA treatment. CTOP blocked EA inhibition of the affective response, but nor-BNI did not. *P<0.05 compared to saline control.

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