Figure 7. Examination of IGF-I plasma and tissue levels.
IGF-I levels were determined in the plasma (A) and hippocampus (B) of young saline rats and old rats treated with either saline or GH. (A) The decrease in plasma IGF-I between young and old saline rats fell short of significance (p = 0.098). Plasma IGF-I levels in old rats treated with GH do not differ significantly from old saline rats, but were significantly lower than in young saline rats p = 0.02 (* = Young Saline significantly different from Old GH). (B) IGF-I levels in hippocampus did not differ with age or GH injection.