Table 1.
Descriptive statistics for the experimental groups for TICV and APOE genotype
| AD | VaD | MA/MCI | Mixed | Control | F-Statistic | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Education-years (s.d.) | 13.12 (2.97) | 12.19 (2.43) | 13.3 (3.06) | 12.72 (3.33) | 12.95 (2.37) | 0.44 (p=.78) | |||||
| Age (s.d.) | 83.17 (6.59) | 83.88 (6.97) | 83.78 (6.87) | 81.14 (6.98) | 76.7 (6.38) | 4.83 (p=.001) | |||||
| M/F | 32/52 | 8/12 | 16/14 | 19/20 | 8/12 | ||||||
| APOE | ε4+ (n=60) | ε4- (n=24) | ε4+ (n=6) | ε4- (n=14) | ε4+ (n=22) | ε4- (n=8) | ε4+ (n=18) | ε4- (n=21) | ε4+ (n=14) | ε4- (n=6) | |
|
|
|||||||||||
| TICV-cm3 | 1413.58 | 1469.36 | 1485.89 | 1483.66 | 1416.89 | 1350.76 | 1506.99 | 1462.81 | 1533.12 | 1445.19 | |
| Males (s.d.) | (103.36) | (128.16) | (223.79) | (87.24) | (88.92) | (99.47) | (187.94) | (138.7) | (46.85) | (94.11) | .98 (p=.43) |
| n=21 | n=10 | n=2 | n=6 | n=12 | n=4 | n=6 | n=13 | n=4 | n=5 | ||
| Total (Males) | 1431.58 (112.92) | 1484.22 (112.21) | 1400.36 (93.01) | 1476.76 (151.93) | 1484.27 (86.02) | 1.58 (p=.19) | |||||
| n=31 | n=8 | n=16 | n=19 | n=9 | |||||||
| TICV-cm3 | 1270.7 | 1333.11 | 1280.27 | 1306.9 | 1361.23 | 1258.32 | 1260.52 | 1188.33 | 1393.02 | 1324.41 | |
| Females (s.d.) | (101.67) | (135.28) | (68.45) | (132.49) | (116.51) | (80.04) | (117.41) | (97.17) | (47.5) | (120.6) | 1.47 (p=.22) |
| n=40 | n=13 | n=3 | n=9 | n=10 | n=4 | n=12 | n=8 | n=2 | n=9 | ||
| Total (Females) | 1286.01 (112.74) | 1300.25 (117.32) | 1260.4 (104.3) | 1231.64 (113.03) | 1336.88 (112.39) | 1.81 (p=.13) | |||||
| n=53 | n=12 | n=14 | n=20 | n=11 | |||||||
| Total TICV-cm3 M/F (s.d.) | 1339.73 (132.54) | 1373.83 (145.46) | 1335.04 (119.98) | 1351.06 (180.91) | 1403.21 (124.19) | .77 (p=..55) | |||||
Legend: TICV-cm3 = total intracranial volume in cubic centimeters; APOE = Apolipoprotein-E; M/F = male/female; AD = Alzheimer disease; VaD = vascular dementia; Mixed = mixed neuropsychiatric group; Control = control group; (s.d.) = standard deviation