Table 1. Results of a genome-wide association study for Japanese patients with SLE.
rsIDa | Chr | Position (bp) | Cytoband | Gene | Alleleb | No. subjects | Allele 1 freq. | OR (95%CI) | P | ||
1/2 | Case | Control | Case | Control | |||||||
rs10168266 | 2 | 191,644,049 | 2q32 | STAT4 | T/C | 891 | 3,384 | 0.37 | 0.27 | 1.59 (1.42–1.78) | 2.7×10−16 |
rs9501626 | 6 | 32,508,322 | 6p21 | HLA region | A/C | 891 | 3,381 | 0.20 | 0.12 | 1.86 (1.62–2.13) | 1.0×10−18 |
rs2230926 | 6 | 138,237,759 | 6q23 | TNFAIP3 | G/T | 891 | 3,377 | 0.11 | 0.069 | 1.75 (1.47–2.08) | 1.9×10−10 |
rs6964720 | 7 | 75,018,280 | 7q11 | HIP1 | G/A | 891 | 3,384 | 0.25 | 0.19 | 1.43 (1.27–1.63) | 1.3×10−8 |
rs2254546 | 8 | 11,381,089 | 8p23 | BLK | G/A | 891 | 3,384 | 0.78 | 0.72 | 1.42 (1.61–1.25) | 4.1×10−8 |
rs6590330 | 11 | 127,816,269 | 11q24 | ETS1 | A/G | 891 | 3,368 | 0.48 | 0.39 | 1.44 (1.30–1.60) | 1.3×10−11 |
SNPs that satisfied the threshold of P<5.0×10−8 were indicated.
Based on forward strand of NCBI Build 36.3.
SLE, systemic lupus erythematosus; OR, odds ratio.