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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Inflamm Bowel Dis. 2011 Oct 21;18(7):1267–1274. doi: 10.1002/ibd.21908

Figure 2.

Figure 2

Figure 2

A. pStat3 and pStat6 expression in normal, chronic active IBD, LGD, HGD and CAC expressed as a percentage of patients with any staining in the epithelial or immune cell compartment. The percentage of patients with pStat3 (+) epithelial cells and/or immune cells was significantly higher in CAC as compared to than in normal patients (P<0.05). The percentage of patients with pStat6 (+) immune cells was significantly higher in normal patients as compared to CAC (P<0.05). The number on each bar is the number of patients examined for each histological diagnosis and cell type (epithelial and immune cell).

B. Mean score for pStat3 and pStat6 expression in normal, chronic active IBD, LGD, HGD and CAC tissue samples from patients with UC. The mean score for epithelial cell and immune cell pStat3 (+) is significantly higher in CAC than in normal patients (P<0.05). Mean score for pStat6 (+) in immune cells is less in CAC than in normal patients (P<0.05). Error bars indicate standard error of the mean.

IBD, inflammatory bowel disease; LGD, low-grade dysplasia, HGD, high-grade dysplasia, CAC, colitis-associated cancer.