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. Author manuscript; available in PMC: 2013 Sep 1.

Published in final edited form as: Addict Biol. 2011 Oct 21;17(5):908–919. doi: 10.1111/j.1369-1600.2011.00392.x

Rate frequency curves for GHR-R null rats (N=6) and WT rats N=5) as a function of stimulation intensity. Panel A: WT rats tested at 75 uA and GHR-R null rats tested at 300 uA show similar rate frequency curves. WT- and GHR-R null rats were not significantly different in terms of total responses or 50% threhold responses. Panel B: GHR-R null rats tested at 100 uA fail to respond for ICSS, whereas WT rats show a typical rate frequency curve. Calculation of threshold response was not possible for GHR-R null rats tested at 100 uA.

Rate frequency curves for GHR-R null rats (N=6) and WT rats N=5) as a function of stimulation intensity. Panel A: WT rats tested at 75 uA and GHR-R null rats tested at 300 uA show similar rate frequency curves. WT- and GHR-R null rats were not significantly different in terms of total responses or 50% threhold responses. Panel B: GHR-R null rats tested at 100 uA fail to respond for ICSS, whereas WT rats show a typical rate frequency curve. Calculation of threshold response was not possible for GHR-R null rats tested at 100 uA.