Table 1.
DR-DQ blocks bearing alleles of the DRB1*08 group. Alleles at DQA1 and DQB1 that associate tightly with alleles of the DRB1*08 group are shown. These haplotype fragments were classified according to their frequencies in different populations [17–31]. Differences in shading denote different DQA1-DQB1 blocks that may associate with different alleles of the HLA-DRB1*08 group.
| DRB1 | DQA1 | DQB1 | frequency overall | exclusive for an ethnic group |
|---|---|---|---|---|
| 08:06 | 01:02 | 06.02 | common | African |
| 08:06 | 05:05 | 03.19 | less common | African (narrow distribution, North African?) |
| 08:04:01 | 04:01 | 03:19 | very common | African |
| 08:04:01 | 05:05 | 03:19 | common | African |
| 08:04:01 | 01:02 | 06:02 | rare | African |
| 08:04:01 | 04:01 | 04:02 | common | African/European |
| 08:01 | 04:01 | 04:02 | very common | European |
| 08:01 | 03:01 | 0302 | rare | European |
| 08:03 | 06:01 | 03:01 | common | European |
| 08:03 | 01:03 | 06:01 | very common | Asian |
| 08:02:01 | 04:01 | 04:02 | very common | American Indian/Asian |
| 08:02:01 | 03:01 | 0302 | common | Asian |
| 08:07 | 04:01 | 04:02 | common | South American Indian |
| 08:11 | 04:01 | 04:02 | common | North American Indian |
| 08:04:04 | 04:01 | 04:02 | common | North American Indian (narrow distribution) |
| 08:04:02 | 04:01 | 04:02 | common | South American Indian (narrow distribution) |