Comparison of registration accuracies between statistical atlas-based registration and the two single atlas-based registrations. Two publicly available mouse atlases, the MOBY phantom [48] and DIGIMOUSE atlas [49], are used for the comparison. The skin, skeleton, and lungs are evaluated based on non-contrast images, while other organs are evaluated based on contrast-enhanced images. (a) Comparison results of Dice coefficient. (b) Comparison results of recovery coefficient of organ volume. (c) Comparison results of surface distance. In each comparison, both mean value and standard deviation across the target subjects are plotted.