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. 2011 Aug 25;22(3):379–388. doi: 10.1093/glycob/cwr110

Table I.

Specific activity of the wild-type and mutant enzymes of β4Gal-T1

Enzyme UDP-GalNAc → GlcNAc (pmol/min/ng)# UDP-GlcNAc → GlcNAc (pmol/min/μg)*
WT-β4Gal-T1 0.02 ND
Y289L-β4Gal-T1 22 ± 5 65 ± 1
R228K-β4Gal-T1 0.67 ± 0.04 ND
R228K-Y289L–β4Gal-T1 29 ± 6 207 ± 8

ND, none detected. The GalNAc-T activity is expressed as per nanograms of protein (#) compared with GlcNAc activity (*), which is per micrograms of protein.