Table I.
Cytokine | WT mice Mean ± SEM pg/ml BALF | Swap-70−/− mice Mean ± SEM pg/ml BALF | ||
---|---|---|---|---|
Saline | OVA | Saline | OVA | |
IL-4 | 3.09 ± 0.43 | 24.77 ± 19.53 | 2.25 ± 0.32 | 4.06 ± 0.93 |
IL-5 | 7.37 ± 1.37 | 62.22 ± 24.77* | 5.8 ± 0.97 | 14.32 ± 4.11*,# |
IL-13 | <0.01 | 16.59 ± 6.03* | <0.01 | 1.9 ± 1.0*,# |
IFNγ | 4.45 ± 0.4 | 3.98 ± 0.9 | 2.59 ± 0.45 | 3.38 0.48 |
IL-2 | 3.54 ± 0.53 | 3.51 ± 0.69 | 2.64 ± 0.35 | 3.02 ± 0.32 |
TNFα | 10.27 ± 1.66 | 24.18 ± 6.0* | 5.98 ± 1.15 | 11.15 ± 2.46*,# |
Eotaxin-1 | 13.27 ± 2.41 | 27.05 ± 8.38 | 11.34 ± 2.85 | 13.43 ± 4.61 |
n = 8 mice for saline groups and 9 mice for OVA-challenged groups
p < 0.05 Saline versus OVA-challenged groups for WT and Swap-70−/− mice
p < 0.05 OVA-challenged Swap-70−/− mice versus OVA-challenged WT mice