TABLE 1.
Clinical characteristics associated with the initial hospitalization according to bronchopulmonary dysplasia (BPD) severity
| All BPD |
BPD severity |
P* | |||
|---|---|---|---|---|---|
| Mild | Moderate | Severe | |||
| Neonatal factors | |||||
| n (% of total) | 322 (NA) | 60 (20.7) | 123 (42.4) | 107 (36.9) | – |
| Birthweight, kg | 1.11±0.46 | 1.17±0.41) | 1.14±0.53 | 1.08±0.43 | 0.1 |
| Gestational age, days | 195.7±21.1 | 196.9±22.3 | 195.6±19.9 | 196.9±21.6 | 0.46 |
| Male sex, n (%) | 190 (59.0) | 32 (53.3) | 66 (53.6) | 70 (65.4) | 0.04 |
| 1 min Apgar score | 4.06±2.36 | 5.17±2.24 | 3.95±2.24 | 3.83±2.39 | 0.001 |
| Mortality, n (%) | 53 (16.7) | 1 (1.7) | 4 (3.3) | 48 (44.9) | <0.0001 |
| Median length of hospital stay, days | 108 | 78 | 117 | 145 | <0.0001 |
| Traditional mechanical ventilation during initial admission | |||||
| Mechanical ventilation, n (%) | 301 (96.5) | 56 (93.3) | 112 (94.2) | 107 (100) | 0.008 |
| Maximal FiO2 | 0.84±2.3 | 0.80±0.23 | 0.83±0.25 | 0.88±0.22 | 0.06 |
| Median duration, days | 42 | 27 | 29 | 72 | <0.0001 |
| Noninvasive positive pressure ventilation during initial admission | |||||
| Noninvasive positive pressure ventilation, n (%) | 122 (37.9) | 34 (56.7) | 49 (39.8) | 38 (35.5) | 0.27 |
| Median duration, days | 4 | 4 | 4 | 7 | 0.28 |
| Supplemental oxygen therapy | |||||
| Median duration†, days | 56 | 18 | 75 | 96 | <0.0001 |
| Discharged home on oxygen, n (%) | 62 (26.1) | 1 (1.7) | 33 (27.7) | 25 (42.4) | <0.0001 |
Data presented as mean ± SD unless otherwise indicated.
*
P value for trend;
†
The duration of supplemental oxygen consists of the entire duration of therapy, both in and out of the hospital. FiO2 Fraction of inspired oxygen; NA Not applicable